The complex interplay between antidepressants and pain medications like tramadol has become an increasingly important area of research, with significant implications for patient care and the ongoing opioid crisis.
Recent studies have shed light on how certain antidepressants may reduce the effectiveness of tramadol in managing pain, potentially leading to increased opioid use and risk of addiction.
This article will explore the mechanisms behind these drug interactions, their clinical significance, and strategies for optimizing pain management
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